Searchable abstracts of presentations at key conferences in endocrinology

ea0044p186 | Obesity and Metabolism | SFEBES2016

Suppression of isoproterenol-induced lipolysis by insulin in rat visceral adipose tissue explants is increased with aging: Consequences on adiposity

Fernandez Alejandro , Pintado Cristina , Gomez Sergio , Arribas Carmen , Gallardo Nilda , Andres Antonio

Although the effect of aging on adipose tissue metabolism have been thoroughly studied for years, changes in the antilipolytic action of insulin in visceral white adipose tissue from aged rats are still not completely understood. By fact, some contradictory data on the inhibition of isoproterenol-induced lipolysis by insulin with aging have been reported. As aging is a significant risk factor for increasing adiposity and the development of obesity, we hypothesized that the inh...

ea0056oc10.4 | Cardiovascular aspects of endocrine diseases | ECE2018

Improvement in the control of hypertension in diabetic patients screened for hyperaldosteronism

Jimenez Ines , Crespo Irene , Cuesta Martin , Elvira Carlos , de Miguel Paz , Santiago Alejandro , Fernandez Luzdivina , de Parayuelo Maria Victoria Saez , Calle Alfonso , Runkle Isabelle

Introduction: Control of hypertension (HT) is essential to reduce cardiovascular events in diabetic patients (DPts). However, studies indicate that only 50% of DPts with treated hypertension present adequate blood pressure (BP) control. Yet Endocrine-Society-Guideline (ESG) screening for primary hyperaldosteronism (PHA) is rarely applied. Furthermore, in patients with essential hypertension (EH), longer-acting hypertension medication (HM) improves 24-hour BP when compared to r...

ea0081p648 | Endocrine-Related Cancer | ECE2022

Spliceosomic landscape across the histological subtypes of lung neuroendocrine neoplasms: a new layer to disentangle tumor Heterogeneity

Blazquez-Encinas Ricardo , Garcia Vioque Victor , Sexton-Oates Alexandra , Trinidad Moreno Montilla Maria , Alors-Perez Emilia , Mangili Federica , Alcala Nicolas , Foll Matthieu , Ibanez Costa Alejandro , Fernandez Cuesta Lynnette , Castano Justo P.

Lung neuroendocrine neoplasms (LungNENs) are highly heterogeneous tumors, which are classified by the WHO according to their histological grade into low grade: Typical Carcinoids (TC) and intermediate grade Atypical Carcinoids (AC), and high-grade: Large Cell Neuroendocrine Carcinoma (LCNEC) and Small Cell Lung Cancer (SCLC). Recently, a number of studies have tried to untangle the molecular features that define each subtype by applying different approaches, including genomic,...